People at higher risk for skin infections often have a weakened immune system (due to age, HIV, chemo, steroids), chronic conditions (like diabetes, eczema, poor circulation, psoriasis), skin damage (cuts, bites, IV drug use), or live/work in crowded or close-contact environments (dorms, sports, healthcare settings). Anyone can get an infection, but breaks in the skin barrier allow bacteria or fungi to enter, increasing vulnerability. 

Treatment for skin infections depends on the type and severity, and may include topical creams, oral antibiotics, or, in severe cases, intravenous antibiotics. Mild infections can often be treated with antibiotic creams, while more serious infections might require oral antibiotics. Viral infections need antiviral treatments, fungal infections require antifungals, and parasitic infections may need antiparasitic medication.  

Skin infection complications range from localized issues like abscesses, scarring, and deeper tissue spread (cellulitis) to severe, life-threatening systemic problems such as sepsis, meningitis, organ failure (heart, lungs, brain), and toxic shock syndrome, especially if the infection is bacterial (like MRSA) or a deep fungal invasion, impacting immunocompromised individuals or those with underlying conditions like diabetes. Serious signs needing urgent care include high fever, confusion, rapid heart rate, and purple skin patches, indicating potential sepsis.